NFKB1 and neoplasm: Our observations that prolonged exposure of ID8-NGL cells to TQ in vitro was associated with persistent NF-κB inhibition (Fig. 1c), and the similar effects of 10 and 30 day TQ treatment on tumor proliferation and apoptosis (Fig. 2c), strongly suggest that direct tumor effects could not explain the deleterious effects of TQ, namely increased ascites formation associated with increased tumor NF-κB activity.