As shown in Figure 3A, sorted RCC-41-PDX-1/CD132+ and RCC-41-PDX-2/CD133+ displayed intermediate levels of ALDH activity (40 and 60% positive cells respectively), while unsorted RCC-41-PDX-2 and sorted RCC-41-PDX-2/CD133− displayed high ALDH activity (> 80% positive cells) (Figure 3A). Here, PROM1 is linked to renal cell carcinoma.