Immunohistochemical comparison of duodenal biopsies from pancreatic-insufficient CF patients and healthy controls revealed an increased infiltration of mononuclear cells expressing the intercellular Adhesion Molecule 1 (ICAM-1), CD-25, Interleukin (IL)-2 and Interferon γ (IFNγ) in the lamina propria of CF patients [5]. The gene discussed is ICAM1; the disease is cystic fibrosis.