More specifically, we assessed whether adipokines are associated with insulin sensitivity/resistance measured with the quantitative insulin sensitivity check index (QUICKI); microvascular baseline (resting) and maximal capillary density; renal and generalized microvascular function, measured with the albumin-to-creatinine ratio (ACR); and endothelial dysfunction measured with the increase in forearm blood flow from resting baseline to maximal vasodilation (FBF % increase). This evidence concerns the gene INS and endothelial dysfunction.