It was recently demonstrated that SRC-2 is activated in response to phosphorylation by the nutrient-sensor mammalian target of rapamycin complex 1 (mTORC1) and this event enables SRC-2 coactivation of SREBP-1 to promote lipogenesis and survival of particularly lipid-reliant prostate cancer cell models4. This evidence concerns the gene NCOA2 and prostate cancer.