Similarly, a generalized decrease in cytophilic IgG directed to both GLURP, MSP-3, AMA-1, MSP-1, and MSP-2 and a significant negative association between Schistosoma infection and IgG1 and IgG3 directed to anti-malarial total extract was reported in individuals infected with Schistosomahaematobium and malaria [24]. Here, IGHG3 is linked to malaria.