BCR and chronic myelogenous leukemia, BCR-ABL1 positive: CML accounts for approximately 15 % of leukaemia case in adults [1, 2], and it is consistently associated with a reciprocal translocation of 9q34 with 22q11, which generates the Breakpoint cluster region/ Abelson oncogene (BCR/ABL) fusion gene that is translated into an oncoprotein (P210BCR/ABL) [2–4].