This may in part be explained by the observation that allergic inflammation decreases local host defense against infections by reducing the expression of antimicrobial peptides and proteins (AMPs), which is mediated at least in part by Th2 cytokines[6,7].These AMPs form an essential element of innate immunity in most multicellular organisms, are mainly produced by neutrophils and epithelial cells, and kill a wide range of bacteria, fungi, viruses and microbes[8]. This evidence concerns the gene ADSL and infection.