Because KCNQ2 [37] and KCNT1 [38] have already been reported to be common and important genes for epileptic encephalopathy, adding the recently reported KCNA2 [39], KCNH1 [40], KCNC1 [41] genes and now the KCNAB1 gene, this led us to pay more attention to the potassium channel genes as a group in epilepsy, especially epileptic encephalopathy. The gene discussed is KCNC1; the disease is Epileptic encephalopathy.