It is noteworthy that ADAMTS12, AMACR, SLC45A2 and C1QTNF3 are associated with cancers, which are all hallmarked by CIN (aneuploidy) (Michor et al. 2005; Llamazares et al. 2007; Lloyd et al. 2012; Abdallah et al. 2013). This evidence concerns the gene ADAMTS12 and cervical squamous intraepithelial neoplasia.