In case of levels above 0.5 ng/mL, the diagnosis of sepsis must be considered.17 In a study in which we provided dosages of PCT and CRP in 52 inpatients, with hemopathies and febrile neutropenia, the PCT average was significantly higher in cases with serious infection (6.7 ng/mL versus 0.6 ng/mL).18 By using a cut-off value of PCT, above 0.245 ng/mL, we observed a 100% of sensitivity and 69.2% of specificity in serious infection, suggesting the use of PCT as a diagnostic marker for severe systemic infection in this population, to the detriment of CRP. Here, CALCA is linked to Sepsis.