CALCA and Decreased total neutrophil count: In a prospective study of 296 patients submitted to HSCT at our university hospital, IL-6, PCT and CRP were evaluated on the day of confirmed neutropenia, on the day of the febrile event, 24 and 72 hours after its onset, and 48 hours or 5 days, in case the fever, persisted.46 The patients were evaluated after the discharge or death within 30 days from the HSCT.