Taking the intersection of common genes and DE genes into consideration, we obtained 19 genes (ALB, ASS1, GSTM3, MAD2L1, ALDH1B1, ALDH4A1, MAPK1, GSTZ1, GATM, FTCD, CCNA2, CENPF, GSTM4, ASNS, CCNB1, NAGS, ACY3, GSTA3, and ESPL1), which might play important roles in the ccRCC development. Here, MAD2L1 is linked to nonpapillary renal cell carcinoma.