First, we assessed the STIM1 expression value between COAD and READ patients, and the expression value of STIM1 was significantly higher in COAD (mean ± SD = 0.144 ± 1.065) than READ (mean ± SD = −0.202 ± 0.906) patients (exact Wilcoxon Mann-Whitney rank sum p = 0.0066, Figure 1B). This evidence concerns the gene STIM1 and colon adenocarcinoma.