SOD2 and breast cancer: Findings of epidemiologic associations between levels of Cav-1 and MnSOD expression and breast cancer outcome led us to perform a set of prospective studies using a tissue microarray containing 36 breast cancer cases and 12 normal tissue controls stratified by histologic grade and clinical stage (TMA-1005, Protein Biotechnologies, Ramona, CA) to detect correlations between Cav-1/MnSOD phenotypes and clinical grade and stage.