CMPK2 encodes a mitochondrial nucleoside monophosphate kinase,26RSAD2 encodes viperin, which is an antiviral protein,27 and RNF144A is an E3 ubiquitin ligase involved in DNA damage repair and apotosis.28 Haploinsufficiency scores indicate that heterozygous loss of these genes is unlikely to cause a neurodevelopmental disorder. The gene discussed is RNF144A; the disease is neurodevelopmental disorder.