However, NMIIA directs convergence and extension tissue movements during the development of the kidney tubules (Lienkamp et al., 2012), accounting for nephropathy in some MYH9-RD cases, characterized by altered NMIIA localization in renal structures and reduced NMIIA expression in podocytes (Ghiggeri et al., 2003). This evidence concerns the gene MYH9 and kidney disorder.