Consistent with this hypothesis, NMIIB and its associated RLCs are increased in atherosclerotic plaques (de la Cuesta et al., 2011; Nikol et al., 1997), and oxidized phospholipids associated with atherosclerosis increase RhoA-driven myosin activity (Essler et al., 1999; Zimman et al., 2010). Here, MYH14 is linked to atherosclerosis.