When we compared the production of TNF-α and IL1-β, PGC-1 and cathelicidin in whole lung tissue from No-EX and SW-EX ICR mice following DRSA infection, we found that DRSA infection had little effect on pulmonary expression of TNF-α and IL-1β in SW-EXE mice, though their baseline levels were already higher than in No-EX mice. The gene discussed is IL1B; the disease is infection.