CHI3L1 and chronic obstructive pulmonary disease: Beyond asthma, other pulmonary or lung-associated disease conditions where YKL-40 levels were found to be increased were chronic obstructive pulmonary disease (COPD) [36,37], idiopathic pulmonary fibrosis [38], tuberculous pleural effusions and pneumonia [39], small-cell lung cancer [40], non-small-cell lung cancer [41], bronchiolitis obliterans syndrome [42], hyperoxic acute lung injury [43], sarcoidosis [44], allergic rhinitis [45], and CF lung disease [46].