Next, we chose some of the 23 RBPs for experimental validation in AML patients with health donors used as normal controls and phorbol myristate acetate (PMA)-induced monocytic differentiation of THP-1 and HL-60 and all transretinoic acid (ATRA)-induced granulocytic differentiation of HL-60 and NB-4 as well as in vitro induction culture of CD34+ HSPCs derived from human umbilical cord blood (UCB). The gene discussed is CD34; the disease is acute myeloid leukemia.