Chk1/2 transcript levels were assessed by quantitative polymerase chain reaction (qPCR) in eight cell lines from B/T-ALL (BV-173, SUP-B15, REH, NALM-6, NALM-19, MOLT-4, RPMI-8402, and CCRF-CEM) (Additional file 1: Figure S1) and in blast cells from 54 adult newly diagnosed ALL cases including 41 (76 %) BCR-ABL1-positive and 13 (23 %) BCR-ABL1-negative cases. The gene discussed is CHEK1; the disease is acute lymphoblastic leukemia.