FSCN1 and metastatic neoplasm: Fascin has been well characterised as an actin-bundling protein that can regulate cell migration as well being an emerging important prognostic marker for metastatic disease (Bi et al., 2012; Gao et al., 2012; Hashimoto et al., 2006; Jayo and Parsons, 2010; Li et al., 2008).