The overexpression of Fibronectin (FN1), Tenascin-C (TNC) and Growth/differentiation factor 15 (GDF15) in melanoma cell lines and of Complement factor B (CFB), Talin-1 (TLN1) and Epidermal growth factor receptor (EGFR) in carcinoma cell lines was confirmed in the conditioned media of the six cell lines (Supplementary Fig. S5). Here, GDF15 is linked to melanoma.