PICSAR and male infertility: To validate whether the accumulation of NLC1-C in the nucleus represses both miR-320a and miR-383 transcripts resulting in hyperactive proliferation of germ cells associated with male infertility, we transfected NT2 cells with pcDNA3.1-NLC1-C or pZW1-sno-NLC1-C plasmid, which stably expresses a nuclear NLC1-C.