Interestingly, the levels of the anti-apoptotic protein, Bcl2, which is known to play a major role in CLL [14, 15] significantly correlated with PARP1 levels (p = 0.003, Spearman's rank (p = 0.009 with Bonferroni correction)) and the relationship was stronger (r = 0.562) (Figure 2C). This evidence concerns the gene BCL2 and B-cell chronic lymphocytic leukemia.