BD patients are most commonly treated with combinations of various immunomodulatory agents including corticosteroids, azathioprine, methotrexate, mycophenolate mofetil, colchicine, and pentoxifylline and biologics such as tumour necrosis factor alpha inhibitors (TNFα-inhibitors; Infliximab) were also found useful [36]. This evidence concerns the gene TNF and Behcet disease.