Multivariable analysis involving NT-proBNP levels in blood serum in the acute phase of the disease, the left ventricular ejection fraction determined 2 to 5 days after admission to hospital, and the age of patients was performed to identify risk factors discernible in the early stage of myocardial infarction which adversely affect the subsequent course of the disease. This evidence concerns the gene NPPB and myocardial infarction.