In a small number of COPD with PH patients (mean PAP: 29.5 ± 5.1 mmHg), the intimal expression of Cav1 was decreased as compared with COPD patients without PAH (mean PAP: 16.7 ± 2.7 mmHg) [27]. The gene discussed is CAV1; the disease is pulmonary arterial hypertension.