Promonin-1 (CD133) serves as such a marker, for example, as it is lost in the urine at the end stage of renal disease (Dimuccio et al., 2014), and additional markers have been defined for a panel of kidney diseases that include diabetic nephropathy (Musante et al., 2014), cardio-renal syndrome (Gonzalez-Calero et al., 2014), autosomal-dominant polycystic kidney disease (ADPKD; Fang et al., 2013; Ben-Dov et al., 2014) and Gitelman's and Bartter syndromes (Corbetta et al., 2015), as well as for following the organ-acceptance after a kidney transplantation (Alvarez et al., 2013). This evidence concerns the gene PROM1 and autosomal dominant polycystic kidney disease.