As we have reported previously 11, 22, TDP‐43 negative, p62‐positive NCI were widely present in the hippocampus and cerebellum of all individuals bearing an expansion in C9orf72 irrespective of clinical or pathological diagnosis, but none were seen in these cells in any of those MND individuals without an expansion in C9orf72, nor in any of the controls. This evidence concerns the gene TARDBP and mild neurocognitive disorder.