ABC proteins that confer drug resistance include P-glycoprotein (genes symbol ABCB1), the multidrug resistance protein 1 (MRP1, gene symbol ABCC1), MRP2 (gene symbol ABCC2) and the breast cancer resistance protein (BCRP, gene symbol ABCG2), induce the drug efflux from tumor cells and decrease cellular drug accumulation47. Here, ABCB6 is linked to neoplasm.