AGBL2 and rheumatoid arthritis: The frequency of positive antibodies in the pre-RA cases compared with controls were: anti-CCP2 (23 % vs 3 %; p < 0.001), anti-cFIB (18 % vs 2 %; p < 0.001), anti-CEP-1 (15 % vs 2 %; p < 0.001), and anti-cVIM (6 % vs 2 %; p < 0.006).