For examples, insulin can be found in human breast cancer tissues [3], and some breast cancers are responsive to insulin and administration of insulin/insulin-like growth factor 1 (IGF-1) receptor family kinase inhibitor or alloxan to produce a status of hypoinsulinemia by destroying the insulin producing pancreatic β-cells may inhibit tumor growth of breast cancer cell line [4]. This evidence concerns the gene IGF1 and Hypoinsulinemia.