Examples of targeted therapies include small molecule inhibitors of the epidermal growth factor receptor (EGFR) pathway in lung cancer (e.g. erlotinib (Tarceva)) and inhibitors of the BCR-ABL tyrosine kinase in chronic myeloid leukemia (e.g. imatinib (Gleevec), dasatinib (Sprycel), and nilotinib (Tasigna)). The gene discussed is EGFR; the disease is chronic myelogenous leukemia, BCR-ABL1 positive.