ELISA analyses demonstrated that both drugs strongly inhibited the secretion of VEGFA in ovarian tumor cells (A2780 cells; MTA: 2.39-fold, DIG-MSK: 2.55-fold, p<0.05; OVCAR-3 cells; MTA: 2.40-fold, DIG-MSK: 3.44-fold, p<0.05) (Fig 9A). Here, VEGFA is linked to ovarian neoplasm.