At 2 years after infection, only one of four Group M animals maintained Gag206–216/Gag241–249-specific CD8+ T cells, whereas all elicited Nef193–203 and Vif114–124 epitope-specific CD8+ T-cell responses, implying that these CD8+ T cells targeting Nef193–203 and Vif114–124 epitopes may contribute to sustained control of viremia in Group M animals. The gene discussed is CD8A; the disease is infection.