IC50 values of HP-β-CyD were determined in 13 leukemia cell lines (Ph+ leukemia; BV173, K562, KBM-5, KBM-5/STI [33], KCL22, MYL and MYL-R [34], AML; HL-60, pre-B cell leukemia; NALM-6, T-cell leukemia; Jurkat and MOLT-4, adult T-cell leukemia; MT1, and MT2). The gene discussed is PML; the disease is acute myeloid leukemia.