HP-β-CyD significantly inhibited the growth of mouse Pro-B cell Ba/F3 cells expressing wild-type BCR-ABL (hereafter Ba/F3 BCR-ABLWT) (Fig 1D), and BV173 cells derived from a human Philadelphia chromosome-positive (Ph+) acute leukemia patient, in a dose- and time-dependent manner (Fig 1E). This evidence concerns the gene BCR and acute leukemia.