CD4 and coinfection: Patients with >10 ml/min/1.73 m2 decrement in eGFR had higher baseline eGFR (p<0.0001), lower CD4 count (p = 0.0058), had more frequent HBV co-infection (p = 0.0070), and had longer exposure to TDF (p<0.0001), compared to those without decrement in eGFR (Table 1).