Except for conventional clinicopathological factors, such as lymph node status, perineural invasion (PNI), pathological grade, and stage, many molecules, such as mucin-1 (MUC1), mesothelin (MSLN), and mucin-2 (MUC2), were studied as prognostic biomarkers that are involved in tumor initiation and development. Here, MSLN is linked to neoplasm.