It is not likely, however, that the BDIV allele of the Nf1 gene—responsible for a large portion of human MPNST—located at 65 Mb on rat chromosome 10 causes the Mss1 resistance effect, as this gene previously did not show association to MPNST incidence and survival time (Roth et al. 2008). Here, NF1 is linked to malignant peripheral nerve sheath tumor.