They are substantially enriched in the Asian MMD population, being present in 37% (RNF213, p.R4810K), 26% (C19orf45, p.M39V), and 20% (ZNF783, p.A267T; MLLT6, p.A198T; APOA1, p.A61T) of Asian MMD cases and absent/infrequent in controls. The gene discussed is APOA1; the disease is multiminicore myopathy.