KCNH1 and acute myeloid leukemia: Strikingly, Kv10.1 was also found to be a key player in regulation of cell division and proliferation [3] and overexpression has been detected at a very high rate (>75 %) in breast, renal and cervical carcinoma cell lines [4] as well as in different human malignancies, for instance colorectal [5] and cervical cancer [6], soft tissue sarcomas [7], acute myeloid leukemia [8], esophageal and gastric cancer [9, 10], head and neck carcinomas [11], ovarian [12], breast, lung and prostate cancer [13].