Besides 7 indels were heterozygous in GK/Slac, one homozygous indel resided in the T2D prior gene Hif1a, but many other rat strains also had this homozygous indel; the other 26 homozygous indels were either located in OR genes or not reported to be associated with T2D. Here, HIF1A is linked to type 2 diabetes mellitus.