Among 192 potential T2D associated genes, seven of them (Tnfrsf1b, Scg5, Fgb, Sell, Dpp4, Icam1, and Pkd2l1) were clearly reported to be T2D prior genes (see Methods for detailed description, S6 File)). The gene discussed is PKD2L1; the disease is type 2 diabetes mellitus.