MYLK and chronic obstructive pulmonary disease: Mycotoxin exposure is another etiological factor in the exacerbation of chronic obstructive pulmonary disease; it increases microbial infection, colonization, or excessive cytokine production via cytoskeletal reorganization mediated by various factors including myosin light chain kinase (MLCK) leading to pulmonary epithelial disruption, one of major pathological events in patients with chronic obstructive pulmonary disease (COPD) [118].