Monocyte recruitment relies in induction of MCP-1 and requires the chemokine receptor CCR2; in their absence mice rapidly succumbed to nonlethal challenge with a normally avirulent strain of T. gondii [19], and the inflammatory monocytes revealed the critical role during the acute infection with T. gondii and neutrophils are not protective but rather contribute to the pathology [20]. Here, CCR2 is linked to infection.