EPCAM and neoplasm: Among the 25 pre-operative biopsy tissues, partial EPCAM-loss foci were observed in 9 of 24 EPCAM-PL cases (38%), and complete negativity of EPCAM expression was observed in one case that had been originally determined to be an EPCAM-CL tumor with EPCAM germline deletion (Figures 4A and 4B).