CORO1A and infection: Further, to investigate the parasite survival when TACO gene is downregulated, macrophages were infected with promastigotes at 1:10 ratio (Figure 7), and subsequently time kinetics of THP-1 cell infection by L. donovani were assessed at early (2 and 4 h), middle (24 and 48 h), and late (72 and 96 h) stages.