NR3C1 and acute lymphoblastic leukemia: Studies using acute lymphocytic leukemic (ALL) cells obtained from patients, as well as 15 T-ALL cell lines grown directly from patients’ cells without prior drug exposure in culture, also indicated that resistance could not be attributed to mutations in GR or variations in levels of its expression (Tissing et al., 2006; Bachmann et al., 2007; Beesley et al., 2009).