Many epidemiological studies with the aim of identifying the role of ERCC2 polymorphisms in the risk of various cancers have been done and different association between Lys751Gln polymorphism and the risk of lung cancer [3–5], glioma [6], colorectal cancer [7], breast cancer [8, 9], and esophageal squamous cell carcinoma [10] has been reported. Here, ERCC2 is linked to cancer.