RNPC3 and amyotrophic lateral sclerosis: Recently, attention has refocused on the possibility that mutant ALS/FTD-associated RBPs might be incorporated into and alter the function of ribonucleoprotein (RNP) granules (Li et al., 2013, Mitchell and Parker, 2014, Ramaswami et al., 2013, Wolozin, 2012).