PDGFRA and glioblastoma: Interestingly, the DEG from the high grade phenotype share a common genetic signature with a proneural type of glioblastoma (Gene set: VERHAAK_GLIOBLASTOMA_PRONEURAL), which is distinguished from other glioblastomas by lower age, better prognosis, PDGFRA expression, and frequent IDH1 mutation (Figure S4) [31].